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The present invention relates to a food composition for inhibiting anticancer drug resistance or ameliorating diseases related stress hormone, including rare ginsenosides CSH1 (Rg6) as an active ingredient. The CSH1 (Rg6) was found to promote combination of BRCA1 and Rad51, suppress the expression of stress hormone-induced γ-tubulin, and suppress resistance to Taxol in a cancer cell. Therefore, the CSH1 (Rg6) is expected to be useful for food for suppressing anti-cancer drug resistance in an anti-cancer therapy, and is expected to be applied also to food for ameliorating stress hormone related diseases.