PHYSIOLOGICALLY ACTIVE MATERIAL COMPLEX, MANUFACTURING METHOD THEREOF AND COSMETIC COMPOSITION USIN

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The present invention discloses a composite containing bio-active material stably combined with a rare-earth hydroxide compound having a layered structure. The bio-active materials in the composite are preserved in terms of long-term stability at high temperature of 50°C or above and the composite maintained in the neutral pH condition to minimize side effects like latent toxicity, irritations, etc. Further, the present invention is useful for a skin-whitening, anti-wrinkle, or anti-aging cosmetic composition containing the composite.