For generating radioactive isotope irradiation target, a method and use of irradiated target irradi

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The invention provides a sintered rare earth metal oxide target for producing a radioisotope in an instrumentation tube of a nuclear power reactor, wherein the sintered target has a density of at least 90 percent of the theoretical density, and wherein the sintered target contains chromium in an amount of from 500 to 2000 μg/g, and Mg and/or Ca in an amount of from 1000 to 6000 μg/g. The sintered target is prepared by providing a rare earth metal oxide powder, blending the rare earth metal oxide powder with chromium oxide, dry granulating and consolidating the powder in a mold to form a spheroidal green body, and sintering the green body in solid phase to form a spheroidal ytterbia target.