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A ventilation system for an operating space accessible to operators in a nuclear installation is intended to allow a supply of decontaminated fresh air for a period of a few hours in the event of serious accidents involving the release of radioactive activity. In particular, the component of radioactive inert gases in the fresh air supplied to the operating space should be as small as possible. For this purpose, the ventilation system has a supply air line that is guided from an external inlet to the operating space, and into which a first fan and a first inert gas adsorber column are connected. An exhaust air line is guided from the operating space to an external outlet, and into which a second fan and a second inert gas adsorber column are connected. A switching device is provided for interchanging the roles of the first and second inert gas adsorber columns.