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The present invention relates to a method for producing a Shinmyung injection agent composition containing a Shinmyung material as an active ingredient. The present invention further relates to a Shinmyung injection agent produced by the method. The Shinmyung injection agent produced by the method of the present invention can relieve pain caused by rare inveterate neuromuscular disease, musculoskeletal pain, central pain and visceral abdominal pain.