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The present invention relates to an external skin application composition with anti-inflammatory and anti-aging effects, containing an extract of Narcissus tazetta cell culture fluid, and to a production method thereof. more specifically, the present invention relates to an external skin application composition for antiinflammation and anti-aging, containing plant cell culture fluid derived from Narcissus tazetta which is a rare plant and culture fluid of an adventitious root or an extract thereof. The present invention relates to a production method thereof. According to the present invention, the external skin application composition containing is not toxic to skin cell and is effective in wrinkle amelioration, wound healing, pore tightening, inhibition of sebum secretion, and reducing acne.COPYRIGHT KIPO 2016