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(57) Abstract : A surgical fastener system can comprise a plurality of fasteners which can be connected to each other by, one, a re - tention matrix which is assembled to the fasteners in order to capture tissue within the fasteners and, two, an alignment matrix configured to hold the fasteners together before the retention matrix is assembled thereto. In various embodiments, the retention matrix and the alignment matrix can each comprise a tissue-contacting surface configured to compress tissue therebetween.