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LUMINESCENT MARKERS, THEIR APPLICATION, METHOD AND KIT OF BIOMOLECULES. The present invention pertains to the field of markers with luminescent properties. Specifically, the marker of the present invention is a nanoparticle comprising rare earth oxides or particle comprising complexes of rare ground layered with a cover material such as for example a organosilane. The nanoparticles covered have a functional group enabling its engagement with an [...]. The present invention further comprises processes for the preparation of markers, as well as a method for detecting biomolecules and a kit comprising the luminescent markers