Derivatives of heteroaryl-alkylcarbamates, preparation method thereof and use of same as FAAH enzym

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C : NRPortbKDCCDAR37532I9_I.DOC14A17/21111 ABSTRACT The invention relates to a compound having general formula (I), wherein : A is selected from among one or more X, Y and/or Z 5 groups; X represents an optionally-substituted methylene group; Y represents a C2-alkenylene, optionally substituted, or a C2 alkynylene; Z represents a C3-, cycloalkyl group; n represents an integer varying between 1 and 7; R1 represents an optionally substituted heteroaryl or naphthalenyl type group; and R7 10 represents a hydrogen atom or a C1.6 alkyl group; R8 represents a hydrogen atom or a C1. 6 alkyl, C3 - 7 cycloalkyl, C3 .7 cycloalkyl C1 .3 alkylene group. The inventive compound takes the form of a base, an acid addition salt, a hydrate or a solvate. Said compounds have an inhibitory activity on the FAAH enzyme. 15 0 Ry R A O, Re 0 0I