Synthesizing 3, 5-dichloro-anisole comprises reacting trichloro-benzene and methanolate of alkaline

文件类型：PDF文档
文件大小：125K
The invention relates to a method for the synthesis of 3, 5- dichloroanisole from the 1, 3, 5-trichlorobenzene, which comprises : a) the reaction of 1, 3, 5-trichlorobenzene and a methanolate of an alkali metal or alkaline-earth metal in a first solvent, aprotic polar; b) the precipitation of the product resulting from step a) in a second solvent; and c) collecting the resulting precipitate; and wherein the first and second solvents are not part substances regarded as carcinogenic, mutagenic and reprotoxic Regulations/or by the (EC) No. 1272/2008 of the European Parliament and of the Council of 16 December 2008. Application : synthesis of 1, 3, 5-triamino -2, 4, 6-trinitrobenzene, the 3, 5- dichloroanisole is an intermediate product.