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A product is described for the prevention and/or treatment of grapevine infections, obtained by the partial or total neutralization of lees originating from winemaking processes, for example by means of alkali or alkali-earth metal oxides or hydroxides; such product generally has a pH comprised between 6.0 and 8.0 and a humidity content of 70% or less; a composition for the prevention and/or treatment of grapevine infections, comprising such product and a process for the preparation of the above-mentioned product, comprising the addition of lees originating from a winemaking process, having a pH generally of 3.0 or less, a basic reactant to bring its pH to a value of 6.0 or above and an optional concentration step to bring the humidity content of the product to a value of 70% or less, are also described.