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A method of manufacturing titanium dioxide particles can produce titanium dioxide particles where a rare earth element is substituted at the titanium sites from which it is possible to highly efficiently take out fluorescence attributable to the rare earth element. The method of manufacturing titanium dioxide particles doped with a rare earth element comprises a step of preparing a liquid precursor containing a titanium source and rare earth metal source, the doping ratio of the rare earth element in the liquid precursor being within a range not less than 0 at % and not more than 5.0 at %, a step of generating thermal plasma and a step of providing the liquid precursor into the thermal plasma.