Medicinal compositions promoting bowel movement

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The present invention relates to uses of adenosine A2 receptor antagonists, in particular, adenosine A2b receptor antagonists, for the preparation of a medicament having defecation-promoting activity, for example for treating, preventing or improving constipation, irritable bowel syndrome or a symptom where defecation is difficult and/or rare, and also for evacuating intestinal tracts at the time of examination of digestive tracts, or before or after an operation. The adenosine A2 receptor antagonists for use according to the invention exhibit a gentle but strong defecation-promoting action without causing diarrhea.