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A method of bioremediating contaminated substrates (e.g. earth materials or waters) utilises a treatment agent selected from the group consisting of : (a) cereal grains which have been used for the production of, and separated from, a wort suitable for use in an alcoholic beverage brewing process, said grains not having been composted subsequent to being separated from the wort; (b) an at least partially dried form of the cereal grains defined in (a); and (c) a biologically active extract of the grains as defined in (a) or (b). The treatment agent may be provided with a coating which is broken down by the pollutant. In a particular embodiment of the invention, the treatment agent is provided in the form of a barrier that may be incorporated into earth material in the path of travel of a contaminant material but upstream of a location (e.g. a body of water) to be protected.