HYBRID NANOPARTICLES INCLUDING AN LN2O3 CORE AND HAVING BIOLIGANDS, AND METHOD FOR PREPARING SAME

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Hybrid nanoparticles including a nanosphere with a mean diameter in the range 2-9 nm, of which at least 90 wt % consists of Ln2O3, where Ln is a rare earth optionally doped with a rare earth or an actinide, or a mixture of rare earths, or else a rare earth/actinide mixture in which at least 50 % of the metal ions are rare-earth ions; a coating around the nanosphere, of which a major part consists of a functionalised polysiloxane, and which has a mean thickness in the range 0.5-10 nm, preferably more than 2 nm but no more than 10 nm; and at least one bioligand grafted by a covalent bond to the polysiloxane coating; and a method for preparing same.