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The xanthene compound and use thereof 发明授权

2023-11-01 2400 127K 0

专利信息

申请日期 2025-06-25 申请号 JP2014087933
公开(公告)号 JP6360345B2 公开(公告)日 2018-07-18
公开国别 JP 申请人省市代码 全国
申请人 五稜化薬株式会社
简介 PROBLEM TO BE SOLVED : To provide a fluorescence probe for measuring activity of molecular species 3A of cytochrome P-450 having excellent cytochrome P-450 molecular species selectivity and excellent detection sensitivity.SOLUTION : There is provided a xanthene-based fluorescent compound represented by the formula (I), where Ris a monovalent group, Ris H or a monovalent group, Rand Rare H, a halogen atom or the like, Ris a monovalent group in which an ether bond of 6-position O-benzyl part of the formula (I) can be oxidation cleaved by cytochrome P-450 molecular species 3A, n is an integer of 1 to 5 and Rs may be same or different when n is 2 or more.


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