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DECONVOLUTION AND DETECTION OF RARE DNA IN PLASMA 发明申请

2023-10-21 2590 9240K 0

专利信息

申请日期 2025-07-08 申请号 WOUS17067871
公开(公告)号 WO2018119216A1 公开(公告)日 2018-06-28
公开国别 WO 申请人省市代码 全国
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
简介 Some embodiments relate to a method for detecting the presence of one or more nucleic acids indicative of a health condition, tissue of origin, germ layer of origin or organ of origin in a mixture of nucleic acids comprising performing methylation analysis on a sample comprising a plurality of nucleic acids and determining whether the sample includes a plurality of methylation haplotype blocks indicative of the presence one or more nucleic acids indicative of a health condition, tissue of origin, germ layer of origin or organ of origin wherein the methylation haplotype blocks comprise a plurality of methylation sites for which the methylation status is coordinated.


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