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ULTRAFINE NANOPARTICLES COMPRISING A FUNCTIONALIZED POLYORGANOSILOXANE MATRIX AND INCLUDING METAL CO 发明申请

2023-04-29 3940 650K 0

专利信息

申请日期 2025-06-25 申请号 US15677167
公开(公告)号 US20180008729A1 公开(公告)日 2018-01-11
公开国别 US 申请人省市代码 全国
申请人 NANOH; UNIVERSITE LYON 1 CLAUDE BERNARD; INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON
简介 The invention relates to novel biocompatible hybrid nanoparticles of very small size, useful in particular for diagnostics and/or therapy. The purpose of the invention is to offer novel nanoparticles which are useful in particular as contrast agents in imaging (e.g. MRI) and/or in other diagnostic techniques and/or as therapeutic agents, which give better performance than the known nanoparticles of the same type and which combine both a small size (for example less than 20 nm) and a high loading with metals (e.g. rare earths), in particular so as to have, in imaging (e.g. MRI), strong intensification and a correct response (increased relaxivity) at high frequencies. The method for the production of these nanoparticles and the applications thereof in imaging and in therapy also form part of the invention.


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