申请日期 | 2025-06-25 | 申请号 | EP13814889 |
公开(公告)号 | EP2935619B1 | 公开(公告)日 | 2017-09-06 |
公开国别 | EP | 申请人省市代码 | 全国 |
申请人 | Roche Diagnostics GmbH; F Hoffmann La Roche AG | ||
简介 | The detection of the presence of rare somatic mutations from a biological sample is often challenging due to the simultaneous presence of a vast excess of wild-type DNA. The present invention describes novel compounds and methods that would allow the enrichment of mutant DNA by depleting amplifiable wild-type DNA. |
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