申请日期 | 2025-09-18 | 申请号 | WOEP14075460 |
公开(公告)号 | WO2015078831A1 | 公开(公告)日 | 2015-06-04 |
公开国别 | WO | 申请人省市代码 | 全国 |
申请人 | ROCHE DIAGNOSTICS GMBH; F HOFFMANN LA ROCHE AG; ROCHE MOLECULAR SYSTEMS INC | ||
简介 | The detection of the presence of rare somatic mutations from a biological sample is often challenging due to the simultaneous presence of a vast excess of wild-type DNA. The present invention describes methods that would allow the enrichment of mutant DNA by depleting amplifiable wild-type DNA. |
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