| 申请日期 | 2025-07-12 | 申请号 | US13836469 |
| 公开（公告）号 | US8889855B2 | 公开（公告）日 | 2014-11-18 |
| 公开国别 | US | 申请人省市代码 | 全国 |
| 申请人 | Bio Thera Solutions Ltd Co | ||
| 简介 | Provided are efficient methods for direct coupling of a maytansinoid with a carboxylic acid to prepare a maytansinoid C-3 ester in high yield using a rare earth metal-based or trifluoromethanesulfonate-based Lewis acid catalyst and a base together with a coupling reagent. Also provided are compositions used in such methods. | ||
|
您还没有登录，请登录后查看下载地址
|
客服热线：
手机版
二维码
