| 简介 |
PROBLEM TO BE SOLVED : To provide a method of promoting wound healing and reducing scar formation, namely a method of promoting healing of an injury or a wound, a method of promoting re-epithelialization of a wound, a method of reducing or preventing scarring during healing of a wound, a method of inhibiting production of TGF-β collagen and collagen induced fibroblast proliferation of a wound of the skin, and a method of improving the appearance of disfiguration.
SOLUTION : A method of healing a wound comprises a step of administering pharmaceutically active H2 relaxin which is recombinant or synthetic in an amount effective in healing of the wound at the concentration of about 1 mg/ml by irrigating the wound, a step of topically administering the H2 relaxin at the concentration of 0.5 to 2.5 mg/ml, or intravenously administering the H2 relaxin at the concentration of 10 to 1000 μg/kg/day.
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