申请日期 | 2025-07-13 | 申请号 | JP2010529879 |
公开(公告)号 | JP5336500B2 | 公开(公告)日 | 2013-11-06 |
公开国别 | JP | 申请人省市代码 | 全国 |
申请人 | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY | ||
简介 | Disclosed are a LDL-like cationic nanoparticle for delivering a nucleic acid gene with improved transfection efficiency and stability, which is surface modified and re-constructed by mimicking lipid components of a natural LDL, a method for preparation of the same, and a method for delivering nucleic acid genes using the same. The cationic nanoparticle of the present invention could effectively be applied in treatment of cancer that overexpress LDL receptors. |
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