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AUTOMATICALLY DETECTING CELLS HAVING NUCLEAR AND CYTOPLASMIC DENSITOMETRIC FEATURES ASSOCIATED WITH 发明授权

2023-03-26 3940 2002K 0

专利信息

申请日期 2025-06-27 申请号 CA2473678
公开(公告)号 CA2473678C 公开(公告)日 2013-11-05
公开国别 CA 申请人省市代码 全国
申请人 VISIONGATE INC
简介 A system and method for rapidly detecting cells (1) of interest using multi- dimensional, highly quantitative, nuclear and cytoplasmic densitometric features (NDFs and CDFs) includes a flow optical tomography (FOT) instrument capable of generating various optical projection images (or shadowgrams) containing accurate density information from a cell, a computer (40) and software to analyze and reconstruct the projection images into a multi- dimensional data set, and automated feature collection and object classifiers. The system and method are particularly useful in the early detection of cancers such as lung cancer using a bronchial specimen from sputum or cheek scrapings and cervical/ovarian cancer using a cervical scraping, and the system can be used to detect rare cells in specimens including blood.


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