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METHODS AND COMPOSITIONS FOR CYTOMETRIC DETECTION OF RARE TARGET CELLS IN A SAMPLE 发明申请

2023-10-31 4510 606K 0

专利信息

申请日期 2025-06-24 申请号 WOUS12053933
公开(公告)号 WO2013036620A1 公开(公告)日 2013-03-14
公开国别 WO 申请人省市代码 全国
申请人 BECTON DICKINSON AND COMPANY; KIRAKOSSIAN Hrair; GOLDBERG Edward; RECKTENWALD Diether
简介 The present disclosure provides cytometric methods for the detection of rare target cells in a sample. In certain aspects, the methods and compositions may facilitate the detection of rare target cells, such as circulating tumor cells (CTCs), in a biological sample such as blood. Aspects of the methods include contacting the sample with first and second binding members that specifically bind to a marker of the rare target cell, and cytometrically assaying the sample for the presence of cells comprising bound first and second binding members to detect the rare target cell in the sample. Also provided are systems, compositions, and kits for practicing the subject methods.


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