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Hybrid nanoparticles with Ln2O3 core and carrying biological ligands, and method of preparation the 发明授权

2023-12-21 4740 1372K 0

专利信息

申请日期 2025-06-25 申请号 US10591465
公开(公告)号 US8357545B2 公开(公告)日 2013-01-22
公开国别 US 申请人省市代码 全国
申请人 Pascal Perriat; Cédric Louis; Christophe Marquette; Rana Bazzi; Stéphane Roux; Olivier Tillement; Gilles Ledoux
简介 The invention concerns hybrid nanoparticles containing : a nanosphere, of mean diameter included in the range from 2 to 9 nm, of which at least 90% by weight consists of Ln2O3 where Ln represents a rare earth, optionally doped with a rare earth or an actinide, or a mixture of rare earths, or a rare earth and actinide mixture, in which at least 50% of the metal ions are rare earth ions, a coating around the nanosphere chiefly consisting of functionalized polysiloxane, having a mean thickness included in the range from 0.5 to 10 nm, preferably greater than 2 nm and no more than 10 nm, andat least one biological ligand grafted by covalent bonding to the polysiloxane coating and their method of preparation.


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