| 申请日期 | 2025-11-25 | 申请号 | AU2011273097 |
| 公开（公告）号 | AU2011273097A1 | 公开（公告）日 | 2013-01-17 |
| 公开国别 | AU | 申请人省市代码 | 全国 |
| 申请人 | Cellectis | ||
| 简介 | (57) Abstract : The present invention concerns novel methods for improving cleavage of DNA by rare-cutting endonucleases, overcoming DNA modification constraints, particularly DNA methylation, thereby giving new tools for genome engineering, par- ticularly to increase the integration efficiency of a transgene into a genome at a predetermined location, including therapeutic ap- plications and cell line engineering. II Ill (88) Date of publication of the international search report : May 2012 | ||
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