客服热线:18202992950

Precursor phase and use thereof for preparing the magnesium salt tetrahydrate of an omeprazole enant 发明授权

2023-03-20 2040 394K 0

专利信息

申请日期 2025-07-12 申请号 EP11164323
公开(公告)号 EP2385046B1 公开(公告)日 2012-09-19
公开国别 EP 申请人省市代码 全国
申请人 PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE; UNIVERSITE DE ROUEN
简介 Precursor phase of magnesium tetrahydrate salt of an omeprazole enantiomer, which has X-ray diffractogram peaks as given in the specification, is claimed. Independent claims are included for : (1) preparing the precursor phase comprising re-mashing a magnesium salt of the enantiomer in amorphous form, in a solvent/water mixture, where the solvent is water-miscible non-alcoholic organic solvents and volume ratio of the solvent to water is 95 : 5-30 : 70; (2) preparing magnesium tetrahydrate salt of an omeprazole enantiomer comprises filtrating and drying a suspension containing the precursor phase; (3) crystals of magnesium tetrahydrate salt of an omeprazole enantiomer obtained by the process; and (4) preparing magnesium salt of omeprazole enantiomer in the dihydrate form A comprises dehydration of crystals of magnesium tetrahydrate salt of an omeprazole enantiomer. ACTIVITY : ACTIVITY -Antiulcer. MECHANISM OF ACTION : None given.


您还没有登录,请登录后查看下载地址


反对 0举报 0 收藏 0 打赏 0评论 0
下载排行
网站首页  |  关于我们  |  联系方式  |  使用协议  |  版权隐私  |  网站地图  |  排名推广  |  广告服务  |  积分换礼  |  网站留言  |  RSS订阅  |  违规举报  |  京ICP备2021025988号-4