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CIRCULATING TUMOR CELL CAPTURE ON A MICROFLUIDIC CHIP INCORPORATING BOTH AFFINITY AND SIZE 发明申请

2023-10-29 2780 7660K 0

专利信息

申请日期 2025-06-25 申请号 WOUS12020555
公开(公告)号 WO2012094642A2 公开(公告)日 2012-07-12
公开国别 WO 申请人省市代码 全国
申请人 ON Q ITY; SKELLEY Alison; SMIRNOV Denis; DONG Yi; MERDEK Keith D; SPROTT Kam; CARNEY Walter; JIANG Chunsheng; HUANG Richard; LUPASCU Ioana
简介 The invention encompasses methods and devices for diagnosing, theranosing, or prognosing a condition in a patient by enriching a sample in rare cells or other particles. The devices can be a microfluidic device comprising an array of obstacles and one or more binding moieties. The devices and methods can allow for enrichment of cells based on size and affinity, recovery of cells or other particles in locations on the microfluidic device, release of cells or other particles from the microfluidic device, flow of sample through the microfluidic device, and retention of rare cells or other particles from a sample obtained from a patient having a condition.


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