| 申请日期 | 2025-06-27 | 申请号 | WOIB11002196 |
| 公开（公告）号 | WO2012001527A3 | 公开（公告）日 | 2012-05-10 |
| 公开国别 | WO | 申请人省市代码 | 全国 |
| 申请人 | CELLECTIS S A; DUCHATEAU Philippe; VALTON Julien; DABOUSSI Fayza | ||
| 简介 | The present invention concerns novel methods for improving cleavage of DNA by rare-cutting endonucleases, overcoming DNA modification constraints, particularly DNA methylation, thereby giving new tools for genome engineering, particularly to increase the integration efficiency of a transgene into a genome at a predetermined location, including therapeutic applications and cell line engineering. | ||
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