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DEVICES AND METHODS TO IMAGE OBJECTS BY TIME DELAY INTEGRATION 发明授权

2023-02-28 4360 613K 0

专利信息

申请日期 2025-06-24 申请号 EP04816174
公开(公告)号 EP1656545B1 公开(公告)日 2012-02-08
公开国别 EP 申请人省市代码 全国
申请人 IMMUNIVEST CORPORATION
简介 Devices and methods for automated collection and image analysis are disclosed that enable identification or classification of microscopic objects aligned or deposited on surfaces. Such objects, e.g. detectably labeled rare target cells, are magnetically or non-magnetically immobilized and subjected to Time Delay Integration imaging (TDI). Incorporation of TDI technology into image cytometry analysis, like CellTracks, makes it possible to image moving objects with very high sensitivity and signal-to-noise ratios. Implementation of TDI camera technology with dual excitation and multispectral imaging of enriched rare cells provides a rapid system for detection, enumeration, differentiation and characterization of imaged rare cells on the basis of size, morphology and immunophenotype.


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