| 申请日期 | 2025-07-09 | 申请号 | JP2010525677 |
| 公开（公告）号 | JPWO2010021289A1 | 公开（公告）日 | 2012-01-26 |
| 公开国别 | JP | 申请人省市代码 | 全国 |
| 申请人 | MARINE BIOTECH INST CO LTD | ||
| 简介 | When ELISA antibody titer dropped in chickens intramuscularly inoculated with an oil vaccine, recombinant HA and NP antigens prepared using gene recombinant technology were orally administered in combination with synthetic oligo CpG as a mucosal adjuvant to the chickens. Even when the immune response induced with the oil vaccine was impaired, the antibody titer was re-induced by orally administering the recombinant HA and NP antigens, and synthetic CpG-ODN in combination. | ||
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