申请日期 | 2025-09-12 | 申请号 | CA2802822 |
公开(公告)号 | CA2802822A1 | 公开(公告)日 | 2012-01-05 |
公开国别 | CA | 申请人省市代码 | 全国 |
申请人 | CELLECTIS | ||
简介 | The present invention concerns novel methods for improving cleavage of DNA by rare-cutting endonucleases, overcoming DNA modification constraints, particularly DNA methylation, thereby giving new tools for genome engineering, particularly to increase the integration efficiency of a transgene into a genome at a predetermined location, including therapeutic applications and cell line engineering. |
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