| 申请日期 | 2025-09-16 | 申请号 | AU2006274689 |
| 公开（公告）号 | AU2006274689B2 | 公开（公告）日 | 2011-11-17 |
| 公开国别 | AU | 申请人省市代码 | 全国 |
| 申请人 | Merck Sharp Dohme Limited | ||
| 简介 | A process for the preparation of a compound of the formula (I) : which process comprises the intramolecular cyclopropanation of an epoxide of the formula (II); in the presence of 0.05 to 0.75 equivalents of a secondary amine base and at least one equivalent of an alkyl lithium base, wherein R, R, R and Rare each hydrogen or C alkyl or R and R are linked to form a C cycloalkyl or C cycloalkenyl ring. | ||
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