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FLUORESCENT OPTICAL DNA SENSOR 发明授权

2023-03-12 4290 847K 0

专利信息

申请日期 2025-09-11 申请号 RU2018107982
公开(公告)号 RU2684276C1 公开(公告)日 2019-04-05
公开国别 RU 申请人省市代码 全国
申请人 Federalnoe gosudarstvennoe avtonomnoe obrazovatelnoe uchrezhdenie vysshego obrazovaniya "Rossijskij universitet druzhby narodov" (RUDN) (RU)
简介 FIELD : chemistry. SUBSTANCE : invention relates to analytical chemistry, namely to study various biomolecules using the method of luminescent imaging of cells and their components. For this purpose, a fluorescent optical DNA sensor is used, consisting of a substrate and a thin film of the DNA phosphor complex adsorbed on it. Substrate is made of zinc oxide of 18×18 mm size, a phosphor are complex oxides of rare-earth elements, such as vanadates, tungstates, molybdates, yttrium and gadolinium rhenates, the content of which in a thin film is from 10-8 to 10-12 mg/ml. EFFECT : invention provides an increase in the sensitivity of a fluorescent optical DNA biosensor for the detection of biomacromolecules at a concentration of less than 10–15 mg/ml. 1 cl, 1 tbl, 2 dwg, 3 ex


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