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Isoxazole-pyridine derivatives as GABA modulators 发明申请

2023-06-25 3140 2427K 0

专利信息

申请日期 2025-06-27 申请号 AU2010244555
公开(公告)号 AU2010244555A1 公开(公告)日 2011-11-03
公开国别 AU 申请人省市代码 全国
申请人 F Hoffmann La Roche AG
简介 The present invention is concerned with novel isoxazole derivatives of formula (I) wherein X, R, R, R and Rare as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of the present invention have affinity and selectivity for GABA A α5 receptor. Further the present invention is concerned with the manufacture of the active compounds of formula (I), pharmaceutical compositions containing them and their use as medicaments.


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