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IMPROVED IMAGING OF IMMUNOMAGNETICALLY ENRICHED RARE CELLS 检索报告

2023-11-08 1560 30K 0

专利信息

申请日期 2025-07-12 申请号 WOUS09044510
公开(公告)号 WO2009143149A3 公开(公告)日 2010-01-14
公开国别 WO 申请人省市代码 全国
申请人 VERIDEX LLC; SCHOLTENS Tycho M; SCHREUDER Frederik; GREVE Jan; TIBBE Arjan; TERSTAPPEN Leon W M M
简介 A method for removing excess unbound ferrofluid and imaging immunomagnetically enriched circulating tumor cells is provided. A vessels having a preformed grooves in the viewing surface is optimally designed for cell alignment and imaging. After separating the unbound particles by centrifugation, an externally-applied force is applied to transport magnetically responsive particle-CTC complex toward the transparent collection wall. The grooved inner surface of the viewing face of the chamber provide uniform distribution of the particles for easy imaging. The invention is also useful in conducting quantitative analysis and sample preparation in conjunction with automated cell enumeration techniques as in quantitative analysis of CTC in disease.


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