| 简介 |
PROBLEM TO BE SOLVED : To provide a compound or fluorescent probe capable of detecting amino acid or peptide cleavage by fluorescence.SOLUTION : The compound is represented by general formula (I) : R-CONH-Ar-R1-(amine-based ligand-rare earth complex) [wherein, R1 is a divalent linkage group binding R-CONH-Ar and the amine-based ligand to each other; Ar is a (substituted) arylene group, (substituted) heteroarylene group, (substituted) aralkylene group or (substituted) heteroaralkylene group; "amine-based ligand" is a ligand containing three or more amino groups each of which may coordinate to a rare earth element, and one or more acidic groups each of which may coordinate, selected from carboxy and sulfo groups, and having a coordination number of 5 or 9; and R-CO is an amino acid group or peptide group].COPYRIGHT : (C)2009, JPO&INPIT |
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