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Hybrid and single chain meganucleases and use thereof 发明授权

2023-02-26 4310 3782K 0

专利信息

申请日期 2025-06-25 申请号 AU2003215869
公开(公告)号 AU2003215869B2 公开(公告)日 2008-04-24
公开国别 AU 申请人省市代码 全国
申请人 CELLECTIS
简介 (57) Abstract : This patent application relates to hybrid and/or single-chain rare-cutting endonucleases, called meganucleases, which recognize and cleave a specific nucleotide sequence, to polynucleotide sequences encoding for said rare-cutting endonucleases, to a vector comprising one of said polynucleotide sequences, t a cell or animal non-human comprising one of said polynucle tide sequences or said rare-cutting endonucleases, to a process for producing one of said rare-cutting endonucleases and any use of the isclosed products and methods. More particularly, this invention contemplates any use of such rare-cutting endonuclease for genetic engineering and gene therapy. European patent (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, H, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR), OAPI patent (BI B J, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published : with international search report before the expiration of the time limit for amending claims and to be republished in the event of receipt amendments For two-letter codes and other abbreviations, refer to the "Guidance Notes on Codes andAbbreviations" appearing at the beginning of each regular issue of the PCT Gazette.


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