申请日期 | 2025-08-14 | 申请号 | WOUS08007947 |
公开(公告)号 | WO2009002529A2 | 公开(公告)日 | 2008-12-31 |
公开国别 | WO | 申请人省市代码 | 全国 |
申请人 | THE JOHNS HOPKINS UNIVERSITY; POMPER Martin Gilbert; RAY Sangeeta; MEASE Ronnie C; FOSS Catherine | ||
简介 | The prostate-specific membrane antigen (PSMA) is increasingly recognized as a viable target for imaging and therapy of cancer. Various 99mTc/Re-labeled compounds were prepared by attaching known Tc/Re chelating agents to an amino- functionalized PSMA inhibitor with or without a variable length linker moiety. Ex vivo biodistribution and in vivo imaging demonstrated the degree of specific binding to engineered PSMA+ PC3 PIP tumors. |
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