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LDL-LIKE CATIONIC NANOPARTICLES FOR DELIVERYING NUCLEIC ACID GENE, METHOD FOR PREPARING THEREOF AND 检索报告

2023-10-20 1790 208K 0

专利信息

申请日期 2025-07-09 申请号 WOKR08006167
公开(公告)号 WO2009051451A3 公开(公告)日 2009-06-04
公开国别 WO 申请人省市代码 全国
申请人 KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY; PARK Tae Gwan; KIM Hyun Ryoung; KIM In Kyoung
简介 Disclosed are a LDL-like cationic nanoparticle for delivering a nucleic acid gene with improved transfection efficiency and stability, which is surface modified and re-constructed by mimicking lipid components of a natural LDL, a method for preparation of the same, and a method for delivering nucleic acid genes using the same. The cationic nanoparticle of the present invention could effectively be applied in treatment of cancer that overexpress LDL receptors.


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