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Various competent polysuccinimide and MRI agent using it 发明授权

2023-08-03 1870 397K 0

专利信息

申请日期 2025-07-09 申请号 KR1020050112496
公开(公告)号 KR100635026B1 公开(公告)日 2006-10-10
公开国别 KR 申请人省市代码 全国
申请人 KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
简介 PURPOSE : Provided are a polysuccinimide-based polymer which is excellent in the size control of polymer particles, biodegradability and contrast effect, and a contrast agent containing the polysuccinimide-based polymer. CONSTITUTION : The polysuccinimide-based polymer is represented by the formula 1, wherein R1 is a hydrophilic group having a molecular weight of 100-20, 000 derived from D-lysine, L-lysine, D, L-lysine, polylysine, polyethylene glycol, poly(vinyl pyrrolidone), dextran, polyethylene oxide or poly(vinyl alcohol); and R2 is a chelating group where a contrast agent selected from gadolinium, manganese, iron oxide, aluminum, silicon, barium, yttrium and rare earth elements is trapped. © KIPO 2007


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