| 简介 |
A novel therapeutic agent for hyperlipidemia, which is an ester compound represented by the formula (i") R3 R 4 (I ") (wherein R z and R 2 are each hydrogen atom or optionally substituted aryl, etc.; X is -CO0or -CON(RI°)-; Rand Rare each hydrogen atom, Ci-C 6 alkyl or Ci-C 6 alkoxy, etc.; R 5, R 6 and R 7 are each hydrogen atom, CI-C 6 alkyl or CI-C 6 alkoxy, etc.; RSand R 9 are each independently hydrogen atom, Ci-C 6 alkyl, -CON(RIS)(R 19) or -COO(RZ°), etc.; ring A, ring B and ring C are each independently aryl or heterocycle residue, etc.; Alk I and Alk 2 are each independently.alkanediyl, etc.; 1 and m are each an integer of 0 or i to 3) or a prodrug thereof, or a pharmaceutically acceptable salt of either. The therapeutic agent selectively inhibits MTP in the small intestine, thus causes no such side effect as a fatty |
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