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The present invention relates to a pharmaceutical composition for innate immunity enhancement and antiviral activity containing a Hovenia dulcis extract as an active ingredient, a health functional food for innate immunity enhancement and antiviral activity containing a Hovenia dulcis extract as an active ingredient, a feed composition for innate immunity enhancement and antiviral activity containing a Hovenia dulcis extract as an active ingredient, and a method for innate immunity enhancement and antiviral activity enhancement in an animal, the method comprising administering a Hovenia dulcis extract to an animal excluding humans, in need of innate immunity enhancement. The Hovenia dulcis-containing composition for innate immunity enhancement and antiviral activity according to the present invention exhibits antiviral activity and innate immunity enhancement efficacy, and thus can be applied for prevention and treatment of bacterial and viral infectious diseases, and can be widely used for a medicine or a health functional food for immunity enhancement and regulation in immunodeficient or immunosuppressed patients and for a feed for innate immunity enhancement and antiviral activity, for the purpose of anti-disease enhancement of animals. Furthermore, the composition for innate immunity enhancement and antiviral activity according to the present invention scarcely causes toxicity or side effects, and thus can be safely used even in the long-term use for prophylactic purposes.