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The invention relates to medicine, and more specifically to pharmaceutical agents which can be used for protecting a skin covering from harmful factors of a chemical and biological nature. What is claimed is a therapeutic dermatological composition for local and external use, comprising an active substance in the form of complex compounds of salts of rare earth elements, quaternary ammonium compounds and a pharmaceutically acceptable carrier, characterized in that said composition comprises an acid-base indicator for colour visualization of a change in the acid-base state of the composition in the event of external factors of a chemical nature acting thereon.