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Method to prepare a catalyst for use in a process for the synthesis of methanol, comprising indium oxide in the form of In2O3, and at least one additional metal selected from a noble metal; and in that the average particle size of said noble metal phase is, preferably at least 0.05 nm, and less than 5 nm as determined by STEM-EDX, characterized in that the catalyst is prepared by co-precipitation of a saline solution at a pH above 8.5 comprising an indium salt and a salt of the at least one additional metal selected from a noble metal and optionally further comprising a salt of the at least one alkaline earth metal.