METHOD OF FORMING MULTIFUNCTIONAL MICROSYSTEM

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FIELD : chemistry.SUBSTANCE : invention relates to field of highly molecular compounds, in particular to methods of obtaining polymer carriers by chemical modification of initial polymer microspheres based on acrolein-styrene copolymer, obtained by emulsifier-free radical polymerisation. Method includes interaction of microspheres with positively charged polyelectrolyte, then, negatively charged polyelectrolyte, which results in formation of polyelectrolyte complex (PEC) on particle surface. After double repetition of procedure of successive PEC precipitation, agents, providing visualisation - semiconductor nanocrystals (quantum points), salts of rare earth metals, magnetic particles, organic dyes are introduced. Positively charged polyelectrolyte is added in quantity 100-200% of the weight of microspheres, with negatively charged polyelectrolyte being added in equimolar quantity. Quantity of visualising agents constitutes 5-40% of polyelectrolyte weight. After that, external polyelectrolyte layer of poly-L-lysine and polyacrylic acid is formed.EFFECT : method makes it possible to obtain carriers of visualising and physiologically active agents, intended for application in field of biotechnology, medicine, veterinary, biochemistry, analytical chemistry, environment monitoring.5 ex