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COMPOUNDS AND METHODS COMPRISING A RHODIUM-BASED INTERCALATOR FOR THE ENRICHMENT OF MUTATED NUCLEIC

2025-06-22 21:241880下载
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The detection of the presence of rare somatic mutations from a biological sample is often challenging due to the simultaneous presence of a vast excess of wild-type DNA. The present invention describes novel compounds and methods that would allow the enrichment of mutant DNA by depleting amplifiable wild-type DNA.


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