CYCLOPENTA(D)PYRIMIDINES AS PROTEIN KINASE AKT INHIBITORS

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FIELD : medicine, pharmaceutics.SUBSTANCE : invention refers to compounds of formula I, as well as to enantiomers and salts thereof, wherein Rand Rare independently specified in H, Me, Et, CH=CH, CHOH, CF, CHFor CHF; Rand Rare independently specified in H or F; Rrepresents H, Me, Et or CF; A is presented by formula : ; wherein G, R, R, R, R, R, R, R, m, n and p are presented in cl. 1 of the patent claim.EFFECT : compounds according to the invention may be used as the protein kinase Akt inhibitors and for treating hyperproliferative diseases, such as cancer.15 cl, 1 tbl, 43 ex