Continuous process for the production of beta-keto esters by Claisen condensation

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(57) Abstract : The invention concerns a continuous process comprising providing to a reaction zone a continuous stream line earth metal amide base and contacting the continuous providing to the or a separate reaction zone a continuous stream of compound (5) with a continuous stream of the to yield an intermediate compound and treating the intermediate OH 0 R OEt (5) for the production of compotmds having the general formula (6) of an alkyl acetate and a continuous stream of an alkali metal or alka- streams together in the reaction zone to yield an enolate compotmd, stream of a compound of formula (5) and contacting the continuous enolate in the or the separate reaction zone at a temperature above 20°C compound of formula (1) with an acid to yield the compound of